BUZZ - Nasdaq top and bottom performing stocks at about 03:45 p.m. EDT Nasdaq 100 .NDX Top Performers Percent Change Arm Holdings PLC ARM.OQ +6.0% PDD Holdings Inc PDD.OQ +5.1% MongoDB Inc MDB.OQ +3.8% PayPal Holdings Inc PYPL.OQ +3.8% Atlassian Corp TEAM.OQ +3.7% Bottom Performers Percent Change Dollar Tree Inc DLTR.OQ -9.9% NVIDIA Corp NVDA.OQ -5.4% Warner Bros Discovery Inc WBD.OQ -2.8% Regeneron Pharmaceuticals Inc REGN.OQ -1.9% Copart Inc CPRT.OQ -1.5% The Nasdaq 100 .NDX gained 8.92 points

U.S. RESEARCH ROUNDUP-Advance Auto Parts, Chewy, Workday Aug 23 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including Advance Auto Parts, Chewy and Workday, on Friday. HIGHLIGHTS * Advance Auto Parts Inc AAP.N : JP Morgan cuts target price to $43 from $55 * Chewy CHWY.N : Piper Sandler raises to overweight from neutral * Intuit Inc INTU.O : Jefferies raises target price to $790 from $770 * Williams-Sonoma Inc WSM.N : TD Co

UPDATE 1-US FDA declines to approve Regeneron's blood cancer therapy Adds details from paragraph 2 onward Aug 20 (Reuters) - The U.S. Food and Drug Administration has declined to approve Regeneron's REGN.O therapy for a common form of blood cancer, the company said on Tuesday. Regeneron was seeking regulatory approval of its therapy, linvoseltamab, in patients with multiple myeloma whose cancer has returned or worsened after at least three prior lines of treatment.

US FDA declines to approve Regeneron's blood cancer therapy Aug 20 (Reuters) - The U.S. Food and Drug Administration declined to approve Regeneron's REGN.O therapy for a common form of blood cancer, the company said on Tuesday. Reporting by Bhanvi Satija, Sneha S K and Nilutpal Timsina in Bengaluru; Editing by Shailesh Kuber

BRIEF-Regeneron Says FDA Issues Complete Response Letter For Co's Linvoseltamab Aug 20 (Reuters) - Regeneron Pharmaceuticals Inc REGN.O : REGENERON PROVIDES UPDATE ON BIOLOGICS LICENSE APPLICATION FOR LINVOSELTAMAB REGENERON PHARMACEUTICALS INC - FDA ISSUES COMPLETE RESPONSE LETTER FOR REGENERON'S LINVOSELTAMAB REGENERON PHARMACEUTICALS INC - LINVO